Category: Notes

Biochemistry (Unit 5)

1. Enzymes Introduction, properties, nomenclature and IUB classification of enzymes Enzyme kinetics (Michaelis plot, Line Weaver Burke plot) Enzyme inhibitors with examples Regulation of enzymes: enzyme induction and repression, allosteric enzymes regulation Therapeutic and diagnostic applications of enzymes and isoenzymes Coenzymes –Structure and biochemical functions

Pathophysiology (Unit 1)

1. Basic principles of Cell injury and Adaptation Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury, Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis & Alkalosis, […]

Pathophysiology (Unit 2)

1. Cardiovascular System Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis). 2. Respiratory system Asthma, Chronic obstructive airways diseases. 3. Renal system Acute and chronic renal failure .

Pathophysiology (Unit 3)

1. Haematological Diseases Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia. 2. Endocrine system Diabetes, thyroid diseases, disorders of sex hormones. 3. Nervous system Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease. 4. Gastrointestinal system Peptic Ulcer.

Pathophysiology (Unit 4)

1. Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease. 2. Disease of bones and joints Rheumatoid arthritis, osteoporosis and gout. 3. Principles of cancer Classification, etiology and pathogenesis of cancer. 4. Diseases of bones and joints Rheumatoid Arthritis, Osteoporosis, Gout.